Google Scholar Crossref , Medline 4. Health economics and cost implications of anxiety and other mental disorders in the United States. Br J Psychiatry Suppl ; Escitalopram treatment improves quality of life of generalised anxiety disorder patients measured by SF Waugh J, Goa K. CNS Drugs ; Google Scholar Crossref , Medline 7. A double-blind comparison of escitalopram and paroxetine in the long-term treatment of generalized anxiety disorder. Ann Clin Psychiatry ; Google Scholar Crossref , Medline 8.
Escitalopram in the treatment of generalized anxiety disorder: Google Scholar Crossref , Medline 9. Treatment of generalized anxiety disorder with escitalopram: J Affect Disord ; Google Scholar Crossref , Medline Escitalopram in the treatment of social anxiety disorder: Br J Psychiatry ; Comorbidity and risk-patterns of depression, generalised anxiety disorder and mixed anxiety-depression in later life: Int J Geriatr Psychiatry ; J Psychopharmacol ; 9: Google Scholar Link Escitalopram can take up to 8 weeks to reach full anti-anxiety effect 9.
Generally, when Lexapro is used for the treatment of depression, GAD, or social anxiety, a period of at least 4 weeks is worthwhile before considering whether to continue to take it or choosing other options 7.
Sometimes, up to 8 weeks are required to reach full effectiveness. How long to stay on Lexapro? The duration of treatment depends on the personal psychiatric history, but is usually at least 6 months.
It will be longer for those who have had two or more previous episodes of depression. Once your depression is gone you may continue escitalopram for up to months.
How to come off Lexapro? The withdrawal results in fewer and less intense discontinuation symptoms than from either paroxetine or venlafaxine. Don't discontinue escitalopram abruptly. Abrupt cessation may result in withdrawal symptoms such as confusion, lethargy, insomnia, tingling or shock like sensations. Onset of these symptoms usually occurs within a week of discontinuation and may last from a few days to several weeks. The authors concluded that escitalopram was more cost-effective than paroxetine, indicating an advantage over paroxetine.
Overall, the methodology was satisfactory and the results were well reported. The authors' conclusions appear to be robust and appropriate. Type of economic evaluation Cost-effectiveness analysis Study objective The aim was to assess the cost-effectiveness of escitalopram compared with paroxetine for generalised anxiety disorder in a primary care setting. Interventions Escitalopram at a daily dose of 10 to 20mg was compared with paroxetine at a daily dose of 20 to 50mg.
A decision tree model was constructed to assess the costs and benefits of the two treatments. The time horizon was 24 weeks. The authors stated that the study was conducted from the perspectives of the provincial health ministry and of society. The clinical evidence was derived from a systematic review of the literature and expert opinions collected via physician questionnaires.
The search details databases, key words, etc. The search identified a key clinical study that provided the main effectiveness data. This was a double-blind, flexible-dose, clinical trial comparing escitalopram against paroxetine. The clinical data derived were the rates of full response, adherence, tolerance, titration, and augmentation.
Monetary benefit and utility valuations: The summary benefit measure was symptom-free days, which were estimated using the decision model. The treatment-related direct costs were those for drugs and physician visits. Productivity losses were valued using the average industrial wage.
It binds to the disorder canada molecule and boosts the concentration of serotonin in the synapse. Med Decis Making ; The price year was reported and discounting was not relevant, as the time horizon was less for one year. Borghi J, Guest J. Escitalopram Scholar CrossrefMedline 7. Escitalopram can take up to 8 weeks to reach generalized anti-anxiety effect 9, cost-effectiveness of escitalopram for generalized anxiety disorder in canada. Eur Psychiatry ; The authors' conclusions appear anxiety be robust and appropriate. Eur Neuropsychopharmacol ; Main cost-effectiveness measures were success response after 12 wk of treatment and no relapse during the following 24 wk and costs.
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